Interventional Treatment of Arrhythmias (Ablation)

Αρχική | Services | Electrophysiology and Arrhythmia Procedures | Interventional Treatment of Arrhythmias (Ablation)

Catheter ablation for the interventional treatment of arrhythmias allows the elimination of the underlying cause of the rhythm disorder, such as an ectopic arrhythmogenic focus or a tachycardia reentry circuit. Its effectiveness depends on the type of arrhythmia and on the characteristics of the electrophysiological disturbance.

The Ablation Procedure

The procedure is performed through puncture of the femoral vein or artery, following administration of local anesthesia. Once the arrhythmogenic substrate is identified, catheters equipped with electrodes at their tips are inserted percutaneously. These electrodes record electrical signals from specific regions of the heart under fluoroscopic guidance.

These steps are often completed more easily if an electrophysiological study has already been performed during the same session.
After catheter placement and induction of tachycardia, a specialized ablation catheter is introduced and positioned at the myocardial sites responsible for initiating the arrhythmia. This catheter may need to be moved from region to region until the precise target area is identified.

Ablation Techniques

Depending on the type of arrhythmia and the anatomical substrate, ablation can be performed using the following techniques:

  • Radiofrequency Ablation (RFA): Delivery of high-frequency electrical current that causes localized thermal necrosis of the myocardial tissue responsible for the arrhythmia.
  • Cryoablation: Using a specialized balloon system that freezes the tissue to achieve ablation.
  • Pulse Field Ablation (PFA): A newer technique that uses electric fields to selectively destroy arrhythmogenic cells, offering significant safety advantages.

Indications for Interventional Arrhythmia Ablation

Ablation is an appropriate treatment option for patients with symptomatic tachyarrhythmias caused by localized foci or reentry circuits that can be safely eliminated.

It is indicated in cases with severe or recurrent symptoms, insufficient response to medical therapy, or intolerance to antiarrhythmic medications.
The most common clinical indications include:

  • Paroxysmal supraventricular tachycardias (AVNRT, AVRT/WPW)
  • Atrial flutter
  • Atrial fibrillation in selected patients
  • Frequent premature ventricular contractions or ventricular tachycardia in the absence of structural heart disease
  • Arrhythmias that recur despite medical treatment
  • Ventricular tachycardia in patients with a previous myocardial infarction or cardiomyopathy

The decision to proceed with ablation is individualized based on the type of arrhythmia, the severity of symptoms, and the patient’s overall clinical profile.

Integration with Electrophysiological Study

When diagnostic electrophysiological studies demonstrate the need for interventional ablation therapy, the ablation can be performed during the same session.

Once mapping of the origin and characteristics of the arrhythmia is completed, therapeutic intervention may follow, provided this is deemed necessary and patient consent has been obtained.

Post-Procedural Course and Follow-Up

After ablation is completed, the patient remains under monitoring for a short period to ensure rhythm stability and to rule out early complications at the puncture site.

In most cases, recovery is smooth, and patients can return to their daily activities within a few days, according to their physician’s instructions.
Clinical follow-up and appropriate cardiology assessment contribute to the long-term evaluation of the procedure’s effectiveness and the timely management of any potential recurrences.

Effectiveness and Prognosis

Catheter ablation has been established as a highly effective treatment for specific tachyarrhythmias, with high success rates when the arrhythmogenic mechanism is accurately identified. Eliminating the ectopic focus or the reentry circuit results in immediate termination of the arrhythmia and sustained improvement in symptoms.

Long-term prognosis depends on the type of arrhythmia, the presence of underlying heart disease, and the structural condition of the myocardium.
In arrhythmias with a well-defined substrate—such as supraventricular tachycardias or typical atrial flutter—ablation provides a definitive cure in the majority of patients.

In more complex arrhythmias, such as atrial fibrillation or ventricular tachyarrhythmias, outcomes are influenced by the extent of underlying cardiac disease, and additional interventions may be required.

Advances in ablation techniques and the growing clinical experience of operators have contributed to improved outcomes and enhanced safety, making ablation an increasingly reliable therapeutic option for a broadening population of patients.

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